The best way to Discover the Greatest Inositol Complement
When in search of the very best inositol complement, there are lots of issues which might be considered.
First, you need to attempt to discover a firm that has good manufacturing practices (GMP certification). Many complement firms will record this on their web sites, however it’s important to do some digging. That’s the reason I listed the GMP certifications on this publish on your comfort.
Second, the very best inositol dietary supplements will probably be freed from any dangerous components or fillers.
Third, you need to attempt to get the best dose for you. Some individuals discover decrease doses are loads, whereas different individuals discover that they require as much as 4 grams a day. You will need to begin with a decrease dose at first to keep away from any potential unwanted effects that may occur because of the therapeutic course of.
Fourth, some individuals discover that having a ratio of 40:1 of Myo-inositol to Chiro-inositol is essential, whereas different individuals discover both kind is sort of efficient for enhancing their well being. This may take some trial and error. For most individuals, nonetheless, both Myo-inositol alone or Chiro-inositol alone is efficient in keeping with 1000’s of reviewers.
If you happen to do select to make use of chiro-inositol, you should utilize a decrease dose, sometimes round 150-300 mg of chiro-inositol per day.
Final however not least, product critiques are taken into consideration as a result of the buyer’s expertise is essential for figuring out if a product is efficient. It’s because some inositol merchandise have 1000’s of critiques.
Greatest Inositol Complement General: Bioclinic Naturals Myoinositol Plus
Bioclinic Naturals Myoinositol Plus is a pure inositol powder complement with pure folate and vitamin B12 added. It is a favourite as a result of it’s additive-free and wholesome for women and men alike. And since it has pure folate, it has some benefits for girls of childbearing age with PCOS too. Because of this, it’s the finest inositol complement for PCOS and other people normally.
Options:
40:1 ratio of myo- to d-chiro inositol 340 mcg of folate from methyl folate1.5 mcg of vitamin B12 as methylcobalamin2 grams of Myo-inositol per serving50 mg of d-chiro-inositol per servingGMP Certified60 servings per container and 129 grams per container$0.48 per serving on the time of this publish on each Amazon and FullscriptFree of synthetic colours, preservatives, and allergen-free. Appropriate for vegetarians
Concerns:
The label is complicated as a result of it says the folate is from methyl folate however lists folic acid below diet details. However it doesn’t include folic acid within the ingredient record.
Greatest Skilled Grade Inositol: Klaire Labs
Klaire Labs Inositol is a highly-rated inositol complement that’s fabricated from D-chiro-inositol. Reviewers like it for enhancing vitality, enhancing sleep, lowering stomach fats, and enhancing blood sugar ranges. Folks report having the ability to use a decrease dose however nonetheless obtain a whole lot of well being advantages with this complement. For all of those causes, that is the very best inositol complement for insulin resistance.
Options:
Allergen freeProfessional grade model that’s trusted by healthcare professionalsThe serving dimension is 150 mg of chiro-inositol per capsule60 servings per containerGMP-certified and third-party licensed for purity and safetyVegetarian$0.70 per capsule on Amazon and it’s barely cheaper on Fullscript
Concerns
Dearer than most manufacturers
Greatest Inositol Complement: PCOS
Theralogix Ovasitol is an inositol product that meets all the standards for the very best inositol complement for fertility. It’s because it will get rave critiques for its use for PCOS and restoration of normal menstrual cycles associated to PCOS. Many reviewers discover much less facial hair and enhancements in pores and skin breakouts after utilizing this complement. For these causes, it’s also among the finest manufacturers of inositol for PCOS.
Options:
4000 mg of myo-inositol per serving and 100 mg of D-chiro inositol40:1 ratio of myo-to-chiro inositolUnflavored powder that may be combined into any liquidNSF licensed for purity and efficiency and GMP certifiedAllergen-free so it is freed from gluten, dairy, soy$0.35 per 2-gram serving on Fullscript and $0.46 per serving on Amazon on the time of this publish
Concerns:
Reviewers recommend beginning with a small dose or half dose to scale back the possibilities of unwanted effects
Biotics Analysis Balanced B8 is a superb inositol complement that reviewers discover superior to different merchandise due to its Myo-inositol & d-chiro inositol 40:1 ratio. Reviewers discover that this ratio helps curb each urge for food and clear up pores and skin zits and even enhance PMS signs. This makes it among the finest myo-inositol and d-chiro-inositol complement manufacturers in the marketplace. I like this product as a result of it discloses its sourcing of inositol which is from carob seed and rice.
Options:
40:1 MI to DCI ratioD-chiro inositol is extracted from carob seedMyoinositol derived from riceThe serving dimension is 1.5 teaspoonsGreat for girls with PCOS or anybody with insulin resistance or metabolic syndrome45 servings per container however accommodates 90 servings should you use 2.5 grams per day$0.50 per serving per day per 2.5 grams by way of Fullscript and $0.80 per serving by way of Amazon on the time of this postGMP-certified and made within the USA
Cenitol by Metagenics is a superb inositol complement fabricated from myo-inositol, magnesium glycinate, and citric acid. Analysis reveals that inositol dietary supplements are helpful for quite a few psychological well being circumstances. The great factor about this complement is that it additionally offers magnesium which can also be calming for the temper. This one stands out as the very best inositol complement for anxiousness based mostly on critiques. Additionally it is the very best inositol complement for sleep in keeping with testimonials.
Options:
4 grams of myoinositol per scoop200 mg magnesium glycinate per scoop800 mg citric acid per scoopHighly rated for anxietyGMP licensed for purity and potencyPractitioner-recommended for moodA 1-month provide on Fullscript is $33 and $49.50 on Amazon on the time of this postNo components or preservatives apart from pure cellulose (fiber)
Concerns:
Dearer than many manufacturers
Greatest Inositol Complement Powder: Protocol for Life Stability Myo Inositol
Protocol for Life Stability Myo Inositol is a extremely rated inositol powder that can also be of nice worth. At simply $0.24 cents per 2-gram serving dimension, this product is inexpensive for nearly anybody. Many reviewers discover that it helps their hormonal issues, together with PCOS, with no unwanted effects. Reviewers additionally rave about how this inositol helps with enhancing their fertility. Of the high-dose inositol dietary supplements, this one will get essentially the most critiques.
Options:
Comprises pure myoinositol as its singular ingredientThe firm complies with Good Manufacturing Follow (GMP) laws of the Pure Merchandise Affiliation (NPA), and the federal cGMP laws of the U.S. Meals and Drug Administration. 76 servings of 6 grams inositol or 228 servings should you use 2 grams per dayNon-GMO and vegetarian/vegan like all inositol supplementsPeople discover this inositol promotes vitality and focus as nicely$0.24 per serving on Fullscript and $0.20 on Amazon on the time of this publish
Concerns:
Doesn’t include D-chiro-inositol however reviewers love its results anyway
Customary Course of Inositol Chewables is nice as a result of you may both swallow the pill or chew it should you favor as a result of it’s naturally sweetened with honey. For this and different causes, this product will get the very best critiques of all inositol dietary supplements on the market. Take note, although, that you’ll have to take 6 tablets a day to equal the doses utilized in medical trials. Nonetheless, reviewers discover that decrease doses assist their signs too.
Options:
Customary Course of is a extremely respected model for decadesGMP CertifiedReviewers even discover this complement helps with sleep qualityA nice choice for youths as a result of it’s chewableContains inositol, honey, and calcium stearate as its solely ingredientAlso accessible in powder kind $0.18 per pill on Fullscript and $0.22 per pill on Amazon on the time of this publish
Concerns:
Decrease dose than most should you use the pill, but additionally accessible in powder kind.
Greatest Inositol Complement Powder for Worth: Zazzee Myo-Inositol
Zazzee Myo-Inositol powder is a superb product in case you are on a good finances however nonetheless desire a high-quality inositol complement. Extremely rated and pure, this myo-inositol complement offers a 6-month provide per container.
Options:
Manufactured within the USA with full NSF and cGMP requirementsFree of allergensContains pure myo-inositol as its solely ingredient2 grams of inositol per scoopOnly $0.18 per serving on Amazon on the time of this post226 servings per container
Concerns:
Doesn’t include D-chiro-inositol however reviewers nonetheless discover this product very efficient
Greatest Inositol Complement Capsules for Worth: Nutricost Inositol
Nutricost Inositol Capsules are nice in case you are on a good finances however nonetheless need all the advantages of inositol. To get 2 grams of inositol, you’ll need to take 4 capsules a day, however this can nonetheless solely value round $0.24 per day. Based mostly on critiques that is the very best inositol complement for weight reduction.
Options:
Extremely rated for one of many myoinositol brands60 servings per bottle$0.24 per serving dimension on Amazon on the time of this postGMP licensed company500 mg of myoinositol per capsuleOther substances are cellulose (fiber), magnesium stearate, and rice flourMany reviewers discover this product very calmingHelps sleep high quality with out grogginessImproves glucose ranges for a lot of
Concerns:
Powders are higher for individuals who don’t prefer to swallow a whole lot of drugs
What’s Inositol?
Inositol is a pure compound referred to as a sugar alcohol which is fabricated from carbohydrates and is sometimes called vitamin B8. It’s naturally discovered within the physique and performs a task in sustaining regular cell operate and construction in our our bodies. Apparently, it additionally helps to control hormones like insulin and intercourse hormones.
There are a number of sorts of inositol and the most typical varieties are:
Myo-inositol D-chiro-inositol
Each of all these inositol assist to enhance insulin sensitivity.
Myo-inositol helps with hormone steadiness and hormone regulation of feminine hormones in comparison with chiro-inositol.
Alternatively, chiro-inositol seems helpful in males by serving to enhance testosterone in keeping with a pilot research. Myo-inositol can also be present in sperm, so each varieties are most likely essential.
As an essential nutrient for development and restore, inositol has been studied for its advantages in lowering respiratory misery in preterm infants whereas extra analysis is required on this space.
Fascinatingly, inositol has many extra advantages as you’ll quickly study.
Why Do Folks Want Inositol Dietary supplements?
The tissue content material of inositol in our our bodies relies upon totally on dietary inositol consumption, suggesting that it’s extra of a vital nutrient than as soon as thought.
And customary dietary habits and way of life modifications trigger our our bodies to wish extra inositol. The components that enhance our physique’s necessities for inositol embrace caffeine, sugar, refined carbohydrate consumption, insulin resistance, diabetes, growing age, and antibiotic drugs.
Inositol-Wealthy Meals
Many contemporary meals have fairly a little bit of inositol which you can match right into a wholesome meal plan.
Inositol-rich meals are:
Cantaloupe ¼ melon: 355 mgOrange 1: 300 mgGrapefruit ½: 199 mgPeas, inexperienced ½ cup 400 mgBeets 1 cup 400 mgOnions ½ cup cooked: 240 mgPotatoes ½ cup mashed 190 mgLiverwerst 1 oz : 100 mgGreen beans ½ cup 193 mgGreat northern beans ½ cup 400 mg
Advantages of Inositol for PCOS
Inositol is likely one of the prime dietary supplements for PCOS. In relation to PCOS, inositol helps many points of this situation. It helps to steadiness feminine hormones whereas additionally lowering insulin resistance which is widespread with PCOS.
In a assessment of 26 medical trials with over 1600 girls, inositol labored nicely to assist handle signs of polycystic ovarian syndrome (PCOS) comparable to hair development.
As one other instance, girls with PCOS utilizing inositol have been 1.8 occasions extra more likely to have a traditional menstrual cycle than girls receiving a placebo. Moreover, using inositol was equal in effectiveness to metformin for its effectiveness on blood sugar management in girls with PCOS.
Not solely that, inositol helped scale back physique mass index (BMI), testosterone, and insulin ranges on this group of ladies members with polycystic ovary points. Moreover, inositol improves the medical being pregnant price and helps normalize menstrual cycles.
Most research used myo-inositol for girls with PCOS. Nevertheless, two research used a ratio of 40:1 myo-inositol to chiro-inositol. One research additionally discovered that utilizing chiro-inositol was additionally efficient for PCOS signs in lean girls.
Inositol might even enhance fertility higher than the drug metformin in girls with PCOS. Nevertheless, not all analysis has confirmed these findings of enchancment in fertility and ovulation.
Inositol Advantages for Diabetes
Inositol has the flexibility to assist make individuals extra insulin-sensitive and lowers blood sugar to extra regular ranges. In actual fact, a assessment of 20 medical trials concluded that inositol considerably reduces fasting blood glucose, improves glucose tolerance, and reduces fasting insulin ranges.
This fascinating compound improves the motion of insulin within the physique.
Gestational diabetes is a dangerous situation for each child and mom. Fascinatingly, inositol reduces the possibilities of getting gestational diabetes whereas additionally enhancing the result of pregnancies in keeping with a assessment of seven medical trials. Utilizing 4 grams of inositol per day was useful for this situation.
Some analysis reveals it really works even higher than the medicine referred to as metformin for individuals with PCOS.
Inositol Advantages for Males
As a result of inositol has blood pressure-lowering advantages and likewise helps scale back fasting insulin and blood sugar ranges, it may be a helpful complement for males in addition to girls.
Moreover, the organs of the male reproductive system are wealthy in myo-inositol which means that it is crucial for males’s reproductive well being. And inositol might enhance testosterone in males in keeping with a pilot research.
Inositol Advantages for Temper
Utilizing inositol additionally is probably going useful for enhancing temper in lots of psychological well being circumstances. It could assist enhance temper for individuals with bipolar dysfunction, obsessive-compulsive dysfunction, and panic dysfunction.
It could work nicely for bipolar dysfunction when mixed with omega 3 fatty acids in keeping with one research though bigger trials are wanted.
Moreover, a assessment of seven research concluded that inositol helps scale back depressive signs, particularly for premenstrual dysphoric dysfunction.
Inositol Advantages for Weight Loss
Many individuals report that inositol helps scale back physique weight. Analysis additionally signifies that inositol could also be helpful for weight reduction. In actual fact, a assessment of 15 managed trials discovered that inositol helps to scale back physique mass index (BMI) with myo-inositol being the best type of inositol for weight reduction.
Folks with increased BMI have been extra more likely to drop pounds with inositol supplementation in addition to individuals older than 40 years of age. Nevertheless, myo inositol for weight reduction results is probably going small, so ought to be used as a part of a wholesome way of life.
Inositol for Blood Strain
Amongst its many advantages, inositol additionally helps to decrease blood stress naturally.
In actual fact, a assessment of seven randomized medical trials discovered inositol efficient for reducing each systolic blood stress and diastolic blood stress.
Doses of 4 grams per day have been only for its blood pressure-lowering results.
What’s the Greatest Form of Inositol?
In relation to well being advantages general, myoinositol is essentially the most researched kind and appears to assist many points of wellness.
Each myo-inositol and chiro-inositol appear efficient with decrease doses of chiro-inositol being useful. Nevertheless, there isn’t sufficient analysis to find out which kind is in the end the very best.
Some analysis combines each types of inositol which appears efficient, however solely 2 research have used the 40:1 ratio of those.
What’s the finest inositol dosage?
For blood stress, doses of 4 grams a day are utilized in analysis. For weight reduction advantages, doses between 1-2 grams per day are used. In relation to PCOS complement research, doses between 300-600 mg of chiro-inositol are efficient particularly when mixed with myo-inositol. Doses of myo-inositol for PCOS of 4000 mg of myo-inositol have been used and have been efficient.
How Lengthy Can I Take Inositol?
Inositol is discovered naturally in meals and there aren’t any security considerations of taking this complement long run. Nonetheless, you need to at all times assessment your complement routine along with your healthcare supplier.
What are Inositol Aspect Results?
Often individuals expertise delicate unwanted effects comparable to fuel, bloating, or nausea with inositol use.
These unwanted effects are solely sometimes seen at very giant doses of higher than 12 grams per day.
Is inositol secure?
There aren’t any identified long-term dangers of taking inositol, however you need to at all times verify along with your healthcare supplier earlier than beginning any new complement.


Heidi Moretti, MS, RD is The Wholesome RD. A registered dietitian for 23 years in addition to a e book creator of the brand new e book Intestine Repair and The Complete Physique Information to Intestine Well being, Heidi has a ardour for useful diet and pure medication. She has researched dietary supplements and pure medication all through her profession. One in all her largest loves helps individuals achieve operate and vitality by tackling the foundation causes of sickness.